Originally published on 11/26/25

On Tuesday, November 25, the Centers for Medicare & Medicaid Services (CMS) announced that it will reduce the cost of 15 prescription drugs for Medicare users in 2027. This cut is expected to save people on a Medicare Part D plan—which covers their medications—millions of dollars. The change is a result of President Joe Biden’s 2022 Inflation Reduction Act, which will also reduce the cost of 10 additional drugs in 2026. Below, we share which medications Medicare users can expect to save on, how experts are reacting to the news and whether there are ways to save on prescriptions in the meantime. 

What to know about the new Medicare drug prices 

In 2022, President Biden signed the Inflation Reduction Act into law, making it possible for the federal government to negotiate the price of prescription drugs for people on Medicare. 

“I know I don’t look it, but I’m around, I’ve been around for 400 years,” Biden joked in 2023, per NBC. “And I’ve been fighting pharma on this since the 1970s. No, not a joke. This time we finally beat Big Pharma.”

Fast forward to now, when that Act allowed the government to lower the prices of 15 drugs, including Ozempic, for Medicare users in 2027. The savings are significant, ranging from 36% to over 84% 

The drugs that will be reduced: 

• Ozempic, Rybelsus and Wegovy, for Type 2 diabetes and weight loss, will go from $959 to $274 in 2027. Negotiated prices for higher doses of Wegovy are $385. 
• Trelegy Ellipta, an asthma treatment, will go from $654 to $175 in 2027. 
• Xtandi, for prostate cancer, will go from $13,480 to $7,004 in 2027. 
• Pomalyst, a chemotherapy drug, will go from $21,744 to $8,650 in 2027.
• Ofev, for idiopathic pulmonary fibrosis, will go from $12,622 to $6,350 in 2027. 
• Ibrance, a breast cancer drug, will go from $15,741 to $7,871 in 2027. 
• Linzess, a chronic constipation drug, will go from $539 to $136 in 2027. 
• Calquence, a cancer drug, will go from $14,228 to $8,600 in 2027. 
• Austedo and Austedo XR, for Huntington’s disease, will go from $6,623 to $4,093 in 2027.
• Breo Ellipta, a COPD drug, will go from $397 to $67 in 2027. 
• Xifaxan, for diarrhea and irritable bowel syndrome, will go from $2,696 to $1,000 in 2027. 
• Vraylar, an antipsychotic drug, will go from $1,376 to $770 in 2027. 
• Tradjenta, a diabetes drug, will go from $488 to $78 in 2027. 
• Janumet and Janumet XR, diabetes drugs, will go from $526 to $80 in 2027. 
• Otezla, a psoriatic arthritis drug, will go from $4,722 to $1,650 in 2027. 

How to save even more on prescriptions  

Since the new drug prices don’t go into effect until 2027, many seniors are worried about the cost of their medications in 2026. There’s some good news on that front, though, because thanks to the Inflation Reduction Act, 10 drugs are going down in price next year. These include: 

• Eliquis, a blood thinner, will go from $521 to $231 in 2026. 
• Xarelto, a blood thinner, will go from $517 to $197 in 2026. 
• Januvia, a diabetes drug, will go from $527 to $113 in 2026. 
• Jardiance, a diabetes drug, will go from $573 to $197 in 2026. 
• Enbrel, a rheumatoid arthritis drug, will go from $7,106 to $2,355 in 2026. 
• Imbruvica, a drug for blood cancers, will go from $14,934 to $9,319 in 2026. 
• Farxiga, a drug for diabetes, heart failure and chronic kidney disease, will go from $556 to $178 in 2026. 
• Entresto, a heart failure drug, will go from $628 to $295 in 2026. 
• Stelara, a drug for psoriasis and Crohn’s disease, will go from $13,836 to $4,695 in 2026.
• Fiasp and NovoLog, two diabetes drugs, will go from $495 to $119 in 2026. 

“It is a historic moment,” former White House domestic policy adviser Neera Tanden said in 2024, per NBC. “Millions of seniors and others on Medicare will soon see their drug costs go down on some of the most common and expensive drugs that treat heart disease, cancer, diabetes…and more.”

Along with those reductions, there are other ways Medicare can save on their medications now and in the future. 

“People can lower prescription costs by shopping smart,” says Cindy George, senior personal finance editor at GoodRx. “A brand-name medication with a GoodRx discount can sometimes be cheaper than the generic copay.” 

“For Medicare recipients, Extra Help and the Medicare Savings Program can dramatically reduce out-of-pocket costs if you qualify,” she continued. “You can also use funds you’ve built up in a Health Savings Account [HSA] to pay Medicare premiums.”

Link to original: https://www.womansworld.com/healthcare/medicare-drug-prices-drop-in-2026-and-2027-see-the-list